Full text is available at the source.
Recent advances in 1,2,3- and 1,2,4-triazole hybrids as antimicrobials and their SAR: A critical review
Recent progress in triazole-based compounds as antimicrobials and how their structure relates to their activity
AI simplified
Abstract
Triazole-containing compounds exhibit a range of biological activities, including potent antimicrobial effects.
- Bacterial resistance to antibiotics poses a significant threat to global health.
- Triazoles, as five-membered nitrogen-containing compounds, exist in two isomeric forms: 1,2,3-triazole and 1,2,4-triazole.
- These compounds have demonstrated various biological activities, including antibacterial, antifungal, and anticancer properties.
- Recent advances have led to the development of antibiotic triazole hybrids with strong antimicrobial activities.
- Structure-activity relationship studies may enhance the understanding necessary for developing new triazole antimicrobials.
AI simplified