Gut Microbiota in the Treatment of Migraine with Acupuncture: A Review

Nov 10, 2025Pain and therapy

Gut Bacteria and Their Role in Treating Migraine with Acupuncture

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Abstract

Migraine is associated with decreased gut microbiota diversity and increased harmful bacteria.

  • Patients with migraine typically exhibit reduced diversity of gut microbiota and a lower abundance of beneficial bacteria.
  • An imbalance in gut microbiota can lead to disturbances in intestinal metabolites and damage to the intestinal and blood-brain barriers.
  • This gut microbiota imbalance is linked to the activation of the trigeminal neurovascular system and increased central inflammation, which may worsen migraine symptoms.
  • Acupuncture has been found to potentially restore gut microbiota diversity and promote beneficial bacteria.
  • The intervention may also decrease harmful metabolites and help maintain the integrity of the intestinal and blood-brain barriers.

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