Annales d'endocrinologie

Sudden liver damage linked to tirzepatide: a surprising side effect needing medical awareness

Updated

Abstract

A case of acute hepatocellular liver injury occurred in a young female after initiating tirzepatide therapy for weight loss.

  • Tirzepatide is a dual receptor agonist approved for type-2 diabetes and weight management.
  • Common side effects include gastrointestinal symptoms such as nausea and vomiting.
  • Reported cases of liver injury associated with tirzepatide are exceedingly rare.
  • The patient experienced recurrent abdominal pain and had a hepatocellular pattern of liver injury.
  • Symptoms resolved and liver enzymes normalized within 3 weeks after presentation.
  • This case highlights the potential for drug-induced liver injury with newer treatments.

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Full Text

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Funding

Competing interests

Disclosure of interest The authors declare that they have no competing interest.
PubMed

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