Biological age predicts spread and survival in gastrointestinal cancer differently depending on patient age

Biological age may better predict cancer outcomes than chronological age.

• Chronological age is linked to cancer risk but does not account for differences in aging among individuals.
• Biological age reflects cumulative functional decline in the body.
• Associations were observed between biological age and disease characteristics in gastrointestinal cancers.
• Biological age may be associated with the presence of metastasis and overall survival in these cancer types.

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