New opportunities for antioxidants in amelioration of neurodegenerative diseases

Antioxidants may play a critical role in mitigating oxidative stress associated with neurodegenerative disorders.

• Oxidative stress has been linked to the development of Alzheimer's, Parkinson's, Huntington's disease, and amyotrophic lateral sclerosis.
• Key antioxidants, including vitamins C and E, glutathione, and polyphenolic compounds, are shown to combat reactive oxygen and nitrogen species.
• Antioxidants may function as both direct scavengers of free radicals and regulators of cellular balance.
• The article explores new antioxidant-based therapy techniques and their mechanisms, including dietary interventions and targeted antioxidant molecules.
• Insights from ongoing clinical studies evaluating antioxidant therapies suggest potential for future treatment development.

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