Association of improved air quality with lower dementia risk in older women

Jan 5, 2022Proceedings of the National Academy of Sciences of the United States of America

Better air quality linked to lower dementia risk in older women

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Abstract

A reduction in fine particulate matter and nitrogen dioxide over a decade is associated with a 20% lower risk of dementia in older women.

  • Improvement in air quality over ten years was linked to decreased dementia risk, showing hazard ratios of 0.80 for both fine particulate matter and nitrogen dioxide.
  • A significant association exists between higher baseline levels of fine particulate matter and an increased risk of dementia.
  • The lower dementia risk linked to improved air quality persisted even after accounting for recent exposure.
  • The findings indicate that long-term air quality improvements in late life may contribute to reduced dementia risk, regardless of age, education, or cardiovascular factors.

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Key numbers

20%
Decrease in dementia risk
Associated with each IQR increment of improved AQ in PM.
13.3 to 10.5 μg/m
PM reduction
Average PM levels before and after the study period.
0.80 per 1.78 μg/m
Dementia risk HR
Hazard ratio for dementia risk associated with AQ improvement.

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