ACR open rheumatology

Autoimmune Disease Risk Linked to Different Diabetes Treatments: GLP-1RA, DPP-4i, and SGLT2i

Updated

Abstract

A comparative evaluation of autoimmune disease incidence was conducted among patients treated with three diabetes medications.

  • Dipeptidyl peptidase-4 inhibitors (DPP-4i), glucagon-like peptide-1 receptor agonists (GLP-1RA), and sodium-glucose cotransporter-2 inhibitors (SGLT2i) are commonly prescribed for type 2 diabetes.
  • The immunologic safety of these medications in relation to autoimmune diseases is currently unclear.
  • This evaluation aims to clarify the incidence of autoimmune diseases among patients using these treatments.

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