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Abstract
Deficiencies in key micronutrients may impair immune regulation and promote inflammation.
- Autophagy is a critical process that connects nutrient availability with cellular quality control and immune regulation.
- Dietary factors can influence autoimmune disease susceptibility by affecting autophagic pathways in immune and metabolic tissues.
- Deficiencies in vitamins and minerals such as vitamin D, zinc, selenium, and omega-3 fatty acids are linked to pro-inflammatory immune responses.
- Obesity and Westernized diets are associated with chronic inflammation, compromised gut health, and enhanced immune system activation.
- Defective autophagy and lysosomal dysfunction can disrupt how the immune system processes antigens, potentially leading to sustained immune activation.
- Strategies like fasting and time-restricted eating may improve autophagy, while high-glycemic diets could hinder this important cellular process.
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