Scientific reports

Immune and brain signaling effects of two Bacteroides bacteria from the human gut

Updated

Abstract

Essence

Bacteroides cellulosilyticus and Bacteroides xylanisolvens may have anti-inflammatory and strain-specific neuromodulatory effects.

Evidence

This in vitro and animal-model study tested two human gut Bacteroides isolates in Caco-2 cells, Caco-2/PBMC cocultures, and Caenorhabditis elegans.

Caveat

Cell and worm gene-expression models do not establish effects on human gut-brain signaling or neuropsychiatric outcomes.

Simplified

Key numbers

17×
Decrease in Levels
Reduction in levels in after treatment with strains.
2 of 4
Decrease in TNF-α Production
Reduction in TNF-α production in co-cultured with treated with .

Full Text

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