The effect of beinaglutide as an glucagon-like peptide-1 receptor agonists on cardiometabolic factors: a systematic review and meta-analysis

Apr 1, 2025Diabetology & metabolic syndrome

Beinaglutide’s effects on heart and metabolism health factors: a review and combined analysis

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Abstract

Beinaglutide significantly reduced weight by 3.74 kg in a meta-analysis of 872 participants across 7 studies.

  • Beinaglutide is associated with a significant decrease in body mass index (BMI) by 1.64 kg/m.
  • Waist circumference (WC) decreased by 3.19 cm with Beinaglutide treatment.
  • Triglyceride (TG) levels were lowered by 0.14 mmol/l due to Beinaglutide.
  • Systolic blood pressure (SBP) showed a reduction of 1.76 mm/Hg with this treatment.
  • Greater reductions in weight and triglycerides were observed with interventions lasting more than 12 weeks.
  • Lower doses of Beinaglutide (less than 0.4 mg) resulted in greater weight loss compared to higher doses.

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Key numbers

-3.74 kg
Weight Reduction
in weight from baseline
-1.76 mm/Hg
Decrease
in
-0.14 mmol/l
Triglyceride Level Reduction
in triglyceride levels

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