A total of 8,994 participants revealed that disability significantly increased the risk of (HR = 1.090).
ADL disability is associated with a higher likelihood of developing depressive symptoms among middle-aged and older adults.
Depressive symptoms are linked to an increased risk of developing ADL disability.
Subgroup analyses indicated that education level, social activity, and existing disability modified the relationship between ADL disability and depressive symptoms.
Age, marital status, and pain were found to influence the association between depressive symptoms and ADL disability.
Sensitivity analyses confirmed the reliability of these findings.
Simplified
This study investigates the bidirectional relationship between (ADL) disability and (DS) among middle-aged and older adults in China, utilizing data from the China Health and Retirement Longitudinal Study (CHARLS) from 2015 to 2018. A total of 8994 participants were analyzed to assess the impact of ADL on the risk of depressive symptoms, while 9673 participants were included to examine the influence of depressive symptoms on the risk of ADL disability. Cox proportional hazards regression models were employed to evaluate these relationships, adjusting for sociodemographic, lifestyle, and health-related covariates. Results revealed that ADL disability significantly increased the risk of depressive symptoms (HR = 1.090, 95% CI 1.058-1.123), and depressive symptoms were associated with a higher risk of ADL disability (HR = 1.033, 95% CI 1.025-1.042). Subgroup analyses demonstrated that factors such as education level, social activity, and disability significantly modified the relationship between ADL and depressive symptoms, while age, marital status, and pain influenced the association between depressive symptoms and ADL. Sensitivity analyses confirmed the robustness of these findings. This study highlights the complex interplay between ADL and depressive symptoms, emphasizing the need for targeted interventions to mitigate the risk of depression and improve functional independence in aging populations.
Key numbers
1.090
Increase in Risk of
Hazard ratio for disability impacting
1.033
Increase in Risk of Disability
Hazard ratio for impacting disability
25%
Cumulative Incidence of
Cumulative incidence rate among participants over three years
Full Text
We can’t show the full text here under this license.
