Recent advances bioactive 1,2,4-triazole-3-thiones

Jan 8, 2015European journal of medicinal chemistry

Recent progress in active 1,2,4-triazole-3-thione compounds

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Abstract

Triazoles, featuring a five-membered ring of two carbon atoms and three nitrogen atoms, are associated with numerous biological activities.

  • Triazoles may exhibit anticonvulsant and antidepressant effects.
  • These compounds are linked to antioxidant and anti-inflammatory properties.
  • Triazoles could possess analgesic and antinociceptive activities.
  • They are also associated with antibacterial, antifungal, and antiviral effects.
  • The review highlights the pharmacological activities of 1,2,4-triazole-3-thiones and indicates potential for future research.

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