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Bioactive glass putty with and without platelet-rich fibrin for periodontal intrabony defects: A prospective comparative study
Using bioactive glass putty with or without platelet-rich fibrin to treat bone defects around teeth: a forward-looking comparison
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Abstract
After 9 months, the test group exhibited a greater amount of bone fill compared to the control group.
- A significant decrease in probing pocket depth (PPD) and an increase in clinical attachment level (CAL) were observed in both treatment groups compared to baseline measurements.
- Modest enhancements in attachment level occurred in the test group receiving the combination of bioactive glass and platelet-rich fibrin (PRF).
- Bioactive glass supports bone regeneration by enhancing the formation of a mineralized extracellular matrix and aiding osteoblast function.
- Platelet-rich fibrin (PRF) may influence cellular processes involved in periodontal regeneration due to its growth factors and leukocytes.
- The combination treatment of bioactive glass and PRF is associated with improved clinical and radiographic outcomes for treating intrabony defects.
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