Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan

Jul 3, 2024FEBS letters

Biochemical factors that balance healthy years and total lifespan

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Longevity & Aging on OpenScience ↗PubMed ↗DOI ↗OA ↗

Abstract

This review highlights the link between mitochondrial function and aging.

Mitochondrial decline is associated with reduced well-being in aging populations.
Targeted interventions to address mitochondrial function may enhance healthspan.
Physical exercise could contribute to healthier aging.
Personalized supplementation strategies based on individual needs may be beneficial.

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In an era of rising global life expectancies, research focuses on enhancing the quality of extended years. This review examines the link between mitochondrial function and aging, highlighting the importance of healthspan alongside lifespan. This involves significant human and economic challenges, with longer lifespans often accompanied by reduced well-being. Addressing mitochondrial decline, exploring targeted interventions, and understanding the complexities of research models are vital for advancing our knowledge in this field. Additionally, promoting physical exercise and adopting personalized supplementation strategies based on individual needs can contribute to healthy aging. The insights from this Perspective article offer a hopeful outlook for future advances in extending both lifespan and healthspan, aiming to improve the overall quality of life in aging populations.

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Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan

Abstract

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