The Journal of bone and joint surgery. American volume

How Biological Age Relates to Adult Spinal Deformity Surgery

Updated

Abstract

Biological age markers provide better risk assessment for adult spinal deformity outcomes than chronological age alone.

  • Systemic frailty tools predict perioperative morbidity and discharge disposition more accurately than age-based models.
  • Muscle and bone assessments can identify patients at higher risk for complications such as implant fracture and pseudarthrosis.
  • Artificial intelligence can automate the measurement of osteosarcopenia and help define alignment targets based on individual profiles.
  • Combining multidimensional biological age profiles into preoperative planning could lead to more personalized surgical strategies.

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