Full text is available at the source.
Biological aging explained by genes, proteins, and harmful molecules
Updated
Abstract
Biological aging is characterized by the accumulation of molecular damage over time.
- Aging is primarily linked to survival beyond the essential lifespan, determined by genetic factors.
- Molecular damage arises from environmental influences, metabolic byproducts, errors in biochemical processes, and nutritional factors.
- Failures in maintenance and repair systems lead to cellular dysfunction and increased vulnerability to diseases.
- A unified theory of aging suggests that homeodynamics, influenced by genetics, environment, and chance, is central to the aging process.
- This theory may provide a framework for developing interventions aimed at preventing or modulating aging.
Simplified