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Abstract
Key parameters like size, charge, and shape of delivery vehicles influence genome editing performance.
- Biophysical properties of viral vectors and lipid nanoparticles significantly affect the efficiency of delivering genome editors.
- Factors such as cargo capacity and stiffness play crucial roles in optimizing delivery systems for precision medicine.
- Different diseases may require tailored delivery approaches due to variations in the biophysical environment around target cells.
- Solid tumors, autoimmune conditions, and cystic fibrosis present unique challenges that necessitate adaptable genome editing strategies.
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