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From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery
From the Blood-Brain Barrier to the Blood-Brain Interface: New Ways to Deliver Drugs to the Brain and Nervous System
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Abstract
Achieving sufficient blood-brain barrier (BBB) penetration remains a significant challenge in developing therapeutics for central nervous system (CNS) disorders.
- The BBB functions as a complex, dynamic interface that adapts to the CNS's needs.
- Physiological changes can influence the permeability and function of the BBB.
- The BBB is associated with various disease processes and may even promote certain conditions.
- Recent research has identified opportunities for innovative approaches to enhance drug delivery to the CNS.
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