International endodontic journal

BMAL1 in Thinking Area Neurons May Reduce Nighttime Pain from Tooth Inflammation

Updated

Abstract

Circadian characteristics of pulpitis-induced pain were explored in mice.

  • Nocturnal exacerbation of pain from pulpitis is observed, impacting sleep and quality of life.
  • The underlying mechanisms of nocturnal pain associated with pulpitis are not well understood.
  • Clock genes may play a role in the modulation of pain during the night.

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