Journal of integrative neuroscience

Brain-Wide Connections of GLP1R Neurons in the Thalamic Reticular Nucleus

Updated

Abstract

A distinct population of GLP1R-expressing neurons has been identified within the thalamic reticular nucleus (TRN).

  • GLP1R is known for its role in regulating metabolism and insulin secretion.
  • Central GLP-1 signaling may influence how sensory information is processed and cognitive functions.
  • The TRN is an important inhibitory center that manages sensory communication between the thalamus and cerebral cortex.
  • The long-range structural connectivity of GLP1R-expressing neurons in the TRN is largely unknown.

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