Breast milk compared to 24% sugar solution for pain relief during procedures in premature babies

Breast milk is not inferior to 24% sucrose for analgesia during heel lance in preterm infants.

• Pain scores were assessed using the Premature Infant Pain Profile-Revised (PIPP-R) during automated heel lance.
• Statistical analysis showed no significant differences in pain scores between the breast milk and sucrose groups across all percentiles.
• The quantile regression estimates indicated a coefficient of 0, with a 95% confidence interval ranging from -0.49 to 0.49.
• Baseline characteristics were similar between the two groups, suggesting comparable starting conditions.

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