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Butyrate: A potential mediator of obesity and microbiome via different mechanisms of actions
Butyrate's possible role in obesity and gut bacteria through different actions
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Abstract
Butyrate may significantly influence metabolic and physiological processes linked to obesity and gut health.
- Butyrate is produced from the fermentation of dietary fibers by gut bacteria.
- It functions primarily as a histone deacetylase inhibitor and engages with signaling pathways involving G protein-coupled receptors.
- Potential benefits of butyrate include promoting gut health and enhancing energy metabolism.
- The specific role of butyrate in obesity is still being explored, with limited human trials available.
- Butyrate may impact the gut-brain axis and influence behavior through microbiome modulation.
- Understanding the metabolic pathways of butyrate is important for developing targeted interventions for metabolic disorders.
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