Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

The C5a protein and its receptor may promote the shift from sudden to chronic kidney damage by increasing cell cleanup processes

Updated

Abstract

Excessive production of complement C5a is detected in acute kidney injury and during chronic kidney disease progression.

  • C5a may be associated with the development of chronic kidney disease.
  • The role of C5a in the progression of kidney disease is not fully understood.
  • Elevated levels of C5a could indicate a potential pathway involved in kidney injury.

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