Diabetes, obesity & metabolism

Heart and kidney risks and safety of GLP-1 medicines in type 2 diabetes patients with BMI under 27

Updated

Abstract

Data on glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in adults with Type 2 diabetes and a body mass index (BMI) below 27 kg/m² is limited.

  • Most evidence for GLP-1 RAs comes from trials involving individuals who are overweight or obese.
  • The effectiveness and safety of GLP-1 RAs in those with a lower BMI remain unclear.
  • Research specifically targeting adults with Type 2 diabetes and lower BMI is sparse.

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