Cardiovascular diseases: a therapeutic perspective around the clock

Apr 23, 2020Drug discovery today

Around-the-Clock Treatment Approaches for Heart and Blood Vessel Diseases

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Abstract

Circadian rhythms regulate various cardiovascular functions, including heart rate and blood pressure.

  • Circadian rhythms are linked to physiological, biochemical, and behavioral processes in the body.
  • Fluctuations in circadian rhythms influence heart rate, blood pressure, cardiac contractility, and metabolism.
  • Modern lifestyles may disrupt internal circadian physiology, potentially increasing the risk of cardiovascular disease.
  • Understanding the mechanisms of circadian dysregulation is an evolving area of research.
  • Chronotherapy may enhance existing treatments for cardiovascular disease and aid in developing new therapies.

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