Nationwide cardiovascular risk categorization: applying the European Society of Cardiology guidelines to the Swedish National Diabetes Register

Of the 320,028 patients with type 2 diabetes, 129,512 had a very high cardiovascular disease risk in 2017.

• Patients with very high cardiovascular disease risk experienced a high incidence of major adverse cardiovascular events at a rate of 75.4 events per 1000 person-years.
• Those with atherosclerotic cardiovascular disease had an even higher incidence, with rates of 136.5 and 90.8 events per 1000 person-years for those with and without elevated glycated hemoglobin, respectively.
• The use of semaglutide in this high-risk group could have potentially avoided 803 major adverse cardiovascular events in 2017.
• This analysis indicates a gap between past prescribing practices and the 2021 European Society of Cardiology guidelines for glucose-lowering medication.

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