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Abstract
Granzyme K (GZMK) may play a role in promoting radiation-induced pulmonary fibrosis (RIPF).
- Radiation-induced pulmonary fibrosis is a severe complication following thoracic radiotherapy.
- Cellular senescence and the senescence-associated secretory phenotype are identified as central drivers of RIPF.
- Granzyme K is an inflammatory amplifier, but its specific role in RIPF is not yet understood.
- Further investigation is needed to clarify how GZMK regulates cellular senescence in the context of RIPF.
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