Central and peripheral clocks in cardiovascular and metabolic function

Apr 19, 2007Annals of medicine

Body and brain internal clocks in heart and metabolism function

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Abstract

The molecular circadian clock influences biological rhythms over a 24-hour schedule.

  • Cardiovascular physiology shows variations throughout the day.
  • The incidence of heart attacks and strokes may vary with the time of day.
  • Disrupted clock function in rodent models has been linked to cardiovascular and metabolic diseases.

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