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Abstract
Dysregulated cGAS-STING signaling is associated with cellular senescence and chronic inflammation.
- cGAS-STING signaling plays a key role in detecting misplaced DNA and initiating inflammatory responses.
- This pathway is important not only for antiviral immunity but also in the context of aging and neuroinflammation.
- Abnormal cGAS-STING activity may drive chronic inflammation and contribute to age-related disorders, especially in the central nervous system.
- Recent research highlights various mechanisms regulating cGAS-STING signaling and its implications for health.
- Current therapeutic approaches aim to modify this pathway to restore immune balance in diseases characterized by chronic inflammation.
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