A chronological age prediction model using clinical biochemistry and hematological data identifies features of biological age in healthy Labrador retrievers

Mar 28, 2026GeroScience

Predicting biological age from blood test data in healthy Labrador retrievers

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Abstract

Analysing over 3 million blood test values from approximately 145,000 dogs revealed significant age-related changes in blood analytes.

  • Age-related changes in blood analytes were observed around 3-6 and 12 years of age.
  • A model using blood analytes and derived ratios was developed to predict age, achieving a mean absolute error of approximately 14.6 months.
  • A greater than 6-month difference between predicted and chronological age was significantly associated with the first diagnosis of common age-related conditions.
  • Findings indicate that standard clinical measures can be utilized to predict age in healthy dogs and may provide insights into biological age and health risks.

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Full Text

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