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How the Body's Biological Clock Affects Drug Responses Over Time
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Abstract
Clock genes may influence the effectiveness and toxicity of drugs based on dosing time.
- Circadian rhythms govern various biological processes, including sleep-wake cycles.
- Drug efficacy and safety can vary depending on the timing of administration.
- Both pharmacokinetics (how the body processes drugs) and pharmacodynamics (how drugs affect the body) are impacted by circadian rhythms.
- Identifying rhythmic markers could enhance the development of chronopharmacotherapy.
- Interactions between drugs and the circadian clock may be relevant for clinical applications.
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