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Chronotherapy in hypertension: a systematic review and meta-analysis of antihypertensive dosing timing on cardiovascular outcomes
Timing blood pressure medicine and its link to heart and blood vessel health: a review and analysis
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Abstract
A total of 42,075 patients were included in the analysis of antihypertensive medication timing.
- No significant differences were found in all-cause mortality between morning and nighttime dosing.
- The risk of myocardial infarction did not differ significantly between the two dosing times.
- Major adverse cardiovascular events showed no significant variance based on the timing of medication.
- Stroke risk was comparable regardless of whether antihypertensive drugs were taken in the morning or at night.
- These results suggest that the timing of antihypertensive medication administration is not associated with major cardiovascular outcomes.
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