Cigarette smoking, type 2 diabetes mellitus, and glucagon-like peptide-1 receptor agonists as a potential treatment for smokers with diabetes: An integrative review

Feb 9, 2019Diabetes research and clinical practice

Cigarette smoking, type 2 diabetes, and potential treatment with glucagon-like peptide-1 drugs for smokers with diabetes

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Abstract

Cigarette smoking in individuals with type 2 diabetes mellitus is associated with twice the likelihood of mortality and negative health outcomes.

  • Tobacco use disorder (TUD) significantly contributes to complications in type 2 diabetes mellitus (DM).
  • Persons with DM who regularly use tobacco products face increased health risks compared to non-smokers.
  • Epidemiological and preclinical biological evidence supports the interconnectedness of TUD and DM.
  • Glucagon-like peptide-1 (GLP-1) may serve as a potential treatment target for addressing TUD in smokers with DM.

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