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Abstract
Aging may impair the functional synchrony of the circadian system, potentially escalating age-related disorders.
- Circadian rhythms are driven by periodic changes in transcriptional activators and translational repressors.
- Technological advancements and constant work schedules have contributed to an increase in circadian disorders.
- Circadian dysfunction is associated with adverse effects on aging and longevity in animal models.
- Non-pharmacological interventions, such as dietary restrictions and physical exercise, may regulate circadian rhythms and support healthy aging.
- Resetting the circadian clock could improve cellular homeostasis and physiology, potentially leading to increased lifespan.
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