PLoS biology

The body’s internal clock controls daily patterns of glucose use

Updated

Abstract

Essence

The circadian clock appears to shape how fruit flies use glucose across the day.

Evidence

A metabolic-tracing study in Drosophila measured time-of-day-dependent glucose pathway activity and disruption in clock and sleep mutants.

Caveat

The abstract reports fly metabolic-pathway data, so it does not establish effects in humans or clinical metabolism.

Simplified

Full Text

What this is

  • The circadian clock regulates glucose metabolism in a time-dependent manner.
  • This perspective discusses how disruptions in circadian rhythms affect glucose utilization pathways.
  • Findings are based on metabolic tracing in Drosophila, highlighting the importance of timing in metabolic processes.

Essence

  • Circadian rhythms play a crucial role in regulating glucose metabolism, with disruptions leading to altered metabolic pathways.

Simplified

Funding

Competing interests

0 of 2
authors report competing interests
2 report none
PubMed

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