Circadian clock gates diurnal glucose utilization

Apr 17, 2026PLoS biology

The body’s internal clock controls daily patterns of glucose use

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Abstract

Metabolic tracing reveals time-of-day-dependent activities of glucose pathways in Drosophila.

The circadian clock influences cellular metabolism and homeostasis.
In Drosophila, glucose metabolic pathways exhibit variations based on the time of day.
Disruptions in these pathways are observed in clock and sleep mutants.

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Full Text

What this is

The circadian clock regulates glucose metabolism in a time-dependent manner.
This perspective discusses how disruptions in circadian rhythms affect glucose utilization pathways.
Findings are based on metabolic tracing in Drosophila, highlighting the importance of timing in metabolic processes.

Essence

Circadian rhythms play a crucial role in regulating glucose metabolism, with disruptions leading to altered metabolic pathways.

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