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Abstract
Disruption of circadian rhythms is associated with glioblastoma (GBM), an aggressive brain cancer.
- Circadian rhythms play a role in regulating the body's physiological functions, including the sleep-wake cycle.
- Alterations in the expression of core circadian genes may contribute to the development of GBM.
- Restoring normal circadian gene function could potentially suppress GBM progression.
- Chronotherapy may enhance the effectiveness of chemotherapy and radiotherapy when aligned with a patient's internal clock.
- Further investigation is required to understand the mechanisms linking circadian rhythms and GBM pathogenesis.
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