Circadian disruption of feeding-fasting rhythm and its consequences for metabolic, immune, cancer, and cognitive processes

Jan 5, 2025Biomedical journal

How Disrupting Daily Feeding and Fasting Patterns May Affect Metabolism, Immunity, Cancer Risk, and Thinking

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Abstract

Circadian disruption (CD) is associated with an increased risk of health alterations, including metabolic syndrome and sleep disruption.

  • The central clock in the brain coordinates daily rhythms with peripheral oscillators in the body.
  • Changes in the timing of light exposure and feeding can lead to disturbances in circadian rhythms.
  • Chronic phase misalignments between the central and peripheral clocks may contribute to various health issues.
  • Animal models of CD show links to conditions such as obesity, chronic inflammation, and cognitive decline.
  • Epidemiological studies suggest similar health risks in humans with altered circadian rhythms.

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