Endocrine

Disrupted daily rhythms of leptin linked to skin inflammation and obesity

Updated

Abstract

Leptin is an adipokine that regulates energy balance and may influence inflammatory skin conditions.

  • Leptin exhibits a circadian rhythm that can be disrupted by variations in eating times and sleep disorders.
  • Dysregulated serum levels of leptin could activate pro-inflammatory pathways.
  • Leptin may modulate appetite and tissue repair processes.
  • There is an association between leptin levels and inflammatory dermatoses, particularly in the context of obesity.

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