Impact of circadian misalignment on energy metabolism during simulated nightshift work

Nov 19, 2014Proceedings of the National Academy of Sciences of the United States of America

How disrupted body clocks affect energy use during simulated night shift work

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Abstract

Total daily energy expenditure decreased by ∼3% on each of the second and third nightshift days.

  • Energy expenditure increased by ∼4% on the transition day to the first nightshift, following an afternoon nap.
  • Energy expenditure decreased by ∼12-16% during scheduled daytime sleep opportunities, despite poor sleep quality.
  • Total daily fat utilization increased on the first and second nightshift days, while carbohydrate and protein utilization decreased on the second nightshift day.
  • Ratings of hunger were lower during nightshift days, even with decreased levels of the satiety hormones leptin and peptide-YY.
  • Findings indicate that working and eating during the biological night may be linked to reduced energy expenditure and increased risk of weight gain.

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