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Daily rhythm of an enzyme’s gene activity in the chicken’s pineal gland inside the body and in lab conditions
Updated
Abstract
A day/night rhythm of hydroxyindole-O-methyltransferase (HIOMT) mRNA levels peaks at midlight phase.
- HIOMT mRNA levels show circadian variations, with high expression at night and a peak during the midlight phase.
- The observed rhythm of HIOMT mRNA persists in constant darkness, indicating an endogenous regulatory mechanism.
- Light exposure during the dark phase stimulates HIOMT mRNA levels in both in vivo and in vitro conditions.
- HIOMT mRNA stability remains unchanged under varying light or dark conditions, suggesting consistency in expression.
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