Life (Basel, Switzerland)

How the Body’s Daily Clock and Gut Bacteria Influence Fat Metabolism

Updated

Abstract

Circadian rhythms significantly influence lipid metabolism, which is essential for maintaining energy balance.

  • Circadian rhythms coordinate processes such as fat synthesis, breakdown, and oxidation.
  • Light exposure, feeding times, diet, hormones, and gut bacteria can affect the regulation of these rhythms.
  • Chronic misalignment of circadian rhythms may increase the risk of obesity and metabolic disorders.
  • The gut microbiota shows significant daily fluctuations and can influence the host's metabolic rhythms.
  • Microbial metabolites and communication between microbes and the host may play a role in regulating metabolism.

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