Research squareJul 3, 2026

Link between disrupted sleep patterns and open-angle glaucoma, influenced by melatonin

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated Jul 4, 2026

Abstract

Circadian rhythm sleep disorders (CRSD) may disrupt neurovascular regulation and are associated with increased risk of open-angle glaucoma.

CRSD may be linked to both open-angle glaucoma (OAG) and ocular hypertension (OHT).
Primary open-angle glaucoma (POAG) may also be more prevalent in individuals with CRSD.
Melatonin's potential modifying effect on these associations was examined.

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