Full text is available at the source.
Abstract
Circadian rhythms are essential for coordinating internal time with the external environment in a 24-h daily cycle.
- The molecular circadian clock significantly influences all physiological processes in mammals.
- Aberrant expression of clock genes is associated with downregulation of targets that control the cell cycle and apoptosis.
- This dysregulation may contribute to genomic instability and promote cancer development.
- Modulating clock genes is recognized as a potential approach for developing effective cancer treatments.
- Understanding circadian rhythms could enhance insights into cancer pathogenesis and progression.
Simplified