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Circadian rhythms and cancer
Body Clock Patterns and Cancer
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Abstract
Circadian rhythms are essential for coordinating internal time with the external environment in a 24-h daily cycle.
- The molecular circadian clock significantly influences all physiological processes in mammals.
- Aberrant expression of clock genes is associated with downregulation of targets that control the cell cycle and apoptosis.
- This dysregulation may contribute to genomic instability and promote cancer development.
- Modulating clock genes is recognized as a potential approach for developing effective cancer treatments.
- Understanding circadian rhythms could enhance insights into cancer pathogenesis and progression.
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