Advances in protein chemistry and structural biology

Body Clock Patterns and Cancer

Updated

Abstract

Circadian rhythms are essential for coordinating internal time with the external environment in a 24-h daily cycle.

  • The molecular circadian clock significantly influences all physiological processes in mammals.
  • Aberrant expression of clock genes is associated with downregulation of targets that control the cell cycle and apoptosis.
  • This dysregulation may contribute to genomic instability and promote cancer development.
  • Modulating clock genes is recognized as a potential approach for developing effective cancer treatments.
  • Understanding circadian rhythms could enhance insights into cancer pathogenesis and progression.

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