Circadian system — A novel diagnostic and therapeutic target in Parkinson's disease?

Jan 31, 2016Movement disorders : official journal of the Movement Disorder Society

The body's internal clock as a new way to diagnose and treat Parkinson's disease?

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Abstract

The circadian system may play a significant role in the multifactorial nature of Parkinson's disease (PD).

  • Parkinson's disease is associated with diurnal fluctuations in both motor and nonmotor symptoms.
  • Emerging evidence suggests that circadian rhythms could influence these fluctuations in PD.
  • Intervening with circadian function may offer new strategies for treating symptoms and slowing disease progression.
  • Existing literature on circadian research in PD indicates a growing interest in this area.

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