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Clinical effectiveness and safety of spinal anaesthesia compared with general anaesthesia in patients undergoing hip fracture surgery using a consensus-based core outcome set and patient-and public-informed outcomes: a systematic review and meta-analysis of randomised controlled trials
Effectiveness and safety of spinal versus general anesthesia for hip fracture surgery using agreed key outcomes and patient-informed measures
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Abstract
Spinal anaesthesia is associated with a 59% lower risk of acute kidney injury compared to general anaesthesia in hip fracture surgery.
- There was no significant difference in the risk of delirium between spinal anaesthesia and general anaesthesia.
- Mortality rates were similar for spinal anaesthesia and general anaesthesia at various time points: in-hospital, 30 days, and 90 days.
- Spinal anaesthesia reduced the risk of acute kidney injury compared to general anaesthesia.
- Few studies reported outcomes defined by patient and public involvement, with most focusing on one to three core outcomes.
- Overall, except for acute kidney injury, no differences were found between spinal and general anaesthesia regarding key outcomes.
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