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Association of CLOCK rs1801260 Polymorphism with Sleep Quality in Residents of the Far North
Link Between a CLOCK Gene Variant and Sleep Quality in People Living in the Far North
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Abstract
In a study of permanent Arctic residents, the TT genotype of the CLOCK gene rs1801260 polymorphism is associated with lower sleep efficiency.
- No significant overall seasonal differences in sleep efficiency were observed (p = 0.487).
- Individuals with the TT homozygote genotype exhibited particularly lower sleep efficiency in spring and summer.
- The TT genotype was identified as the sole significant predictor of sleep efficiency (β = -0.215; p = 0.029).
- The findings suggest a genetic influence on sleep quality among Arctic residents.
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