Coffee, Tea, and Fatal Oral/Pharyngeal Cancer in a Large Prospective US Cohort

Intake of >4 cups/day of caffeinated coffee is associated with a 49% lower risk of oral/pharyngeal cancer death.

• A total of 868 deaths due to oral/pharyngeal cancer were observed during 26 years of follow-up among 968,432 participants.
• Each additional cup of caffeinated coffee consumed daily is linked to a dose-related decline in the risk of oral/pharyngeal cancer death.
• The reduced risk associated with caffeinated coffee intake was consistent across different groups, including varying sex, smoking status, and alcohol use.
• For decaffeinated coffee, an inverse association for >2 cups/day was suggested, though findings were not statistically conclusive.
• No significant association was found between tea drinking and oral/pharyngeal cancer mortality.

AI simplified