American journal of epidemiology

Coffee and tea drinking linked to risk of deadly mouth and throat cancer in a large US group

Updated

Abstract

Intake of >4 cups/day of caffeinated coffee is associated with a 49% lower risk of oral/pharyngeal cancer death.

  • A total of 868 deaths due to oral/pharyngeal cancer were observed during 26 years of follow-up among 968,432 participants.
  • Each additional cup of caffeinated coffee consumed daily is linked to a dose-related decline in the risk of oral/pharyngeal cancer death.
  • The reduced risk associated with caffeinated coffee intake was consistent across different groups, including varying sex, smoking status, and alcohol use.
  • For decaffeinated coffee, an inverse association for >2 cups/day was suggested, though findings were not statistically conclusive.
  • No significant association was found between tea drinking and oral/pharyngeal cancer mortality.

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