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Use of comprehensive geriatric assessment (CGA) to define frailty in geriatric oncology: Searching for the best threshold. Cross-sectional study of 418 old patients with cancer evaluated in the Geriatric Frailty Clinic (G.F.C.) of Toulouse (France)
Using detailed health assessments to identify frailty in older cancer patients: Finding the best cutoff in a study of 418 patients
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Abstract
In a study of 418 cancer patients aged 82.8 years, a threshold of 4 impaired geriatric domains was identified as associated with frailty status.
- Of the patients, 7.9% were classified as robust, 37.1% as pre-frail, and 55% as frail.
- Significant differences were observed in activities of daily living (ADL), instrumental activities of daily living (IADL), nutrition, cognition, and polypharmacy across the frailty groups.
- Frail patients exhibited a greater average number of impaired geriatric domains compared to pre-frail and robust patients (4.5 ± 1.5 vs. 2.8 ± 1.6 vs. 2.1 ± 1.2).
- The sensitivity and specificity of the threshold for identifying frailty were 77.39% and 67.55%, respectively.
- The area under the curve for the ROC analysis was 79.6%, indicating a good level of discrimination for frailty detection.
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