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Abstract
A trivalent multi-epitope mRNA vaccine targeting three mosquito-borne encephalitis viruses has been computationally designed.
- Western equine encephalitis virus (WEEV), Eastern equine encephalitis virus (EEEV), and Venezuelan equine encephalitis virus (VEEV) are associated with severe encephalitis in humans and horses.
- No licensed vaccines are currently available for routine prevention of these viruses in humans.
- The proposed vaccine aims to provide a solution for the prevention of infections caused by these neurotropic alphaviruses.
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