Impact of continuous positive airway pressure treatment on myocardial performance in patients with obstructive sleep apnea. A conventional and tissue Doppler echocardiographic study

Jul 4, 2014Sleep & breathing = Schlaf & Atmung

Continuous positive airway pressure treatment and heart function in obstructive sleep apnea patients

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Abstract

After 12 months of continuous positive airway pressure (CPAP) therapy, significant improvements were noted in several cardiac and somatometric parameters among 31 patients with obstructive sleep apnea.

  • Pulmonary artery systolic pressure decreased significantly after CPAP treatment (p < 0.001).
  • Reductions in right ventricular diameter (p = 0.012), inferior vena cava diameter (p = 0.005), and right ventricular wall thickness (p = 0.006) were observed.
  • Tricuspid annular plane systolic excursion values increased significantly (p = 0.048), indicating improved right heart function.
  • Tissue E/A ratio at the tricuspid annulus also showed significant improvement (p = 0.01).
  • Left ventricular mass was reduced significantly (p < 0.001).
  • Body mass index and waist diameter decreased significantly (p < 0.001 for both) alongside improvements in the apnea-hypopnea index.

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